MP03-Lupus

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Nuestro grupo está centrado en el Riesgo Cardiovascular en las Enfermedades Autoinmunes Sistémicas.

Líneas de investigación

Ejercicio físico y LES
Riesgo Cardiovascular en otras enfermedades autoinmunes sistémicas distintas a LES
Riesgo cardiovascular en lupus eritematoso sistémico

JUAN DIEGO MEDIAVILLA GARCIA

NURIA NAVARRETE NAVARRETE

GERMAN PRADOS GARCIA

ANA ROSALES MARTIN

JOSE MARIO SABIO SANCHEZ

JOSE ANTONIO VARGAS HITOS

MONICA ZAMORA PASADAS

ANTONIO DIAZ CHAMORRO

LAURA JAIMEZ GAMIZ

da Silva, JG; Peralta-Ramirez, MI; Navarrete-Navarrete, N; Silva-Silva, D; Wendt, GW; Caballo, VE

Psychometric properties of Self-Efficacy to Regulate Eating Habits (SEREH) scale

REVISTA ESPANOLA DE NUTRICION HUMANA Y DIETETICA, 2019;

Sola-Rodriguez, S; Gavilan-Carrera, B; Vargas-Hitos, JA; Sabio, JM; Morillas-de-Laguno, P; Soriano-Maldonado, A

Physical Fitness and Body Composition in Women with Systemic Lupus Erythematosus

MEDICINA-LITHUANIA, 2019;

Garcia-Hernandez, FJ; Castillo-Palma, MJ; Tolosa-Vilella, C; Guillen-del Castillo, A; Rubio-Rivas, M; Freire, M; Vargas-Hitos, JA; Todoli-Parra, JA; Rodriguez-Carballeira, M; Espinosa-Garriga, G; Colunga-Arguelles, D; Ortego-Centeno, N; Trapiella-Martinez, L; Rodero-Roldan, MM; Pla-Salas, X; Perales-Fraile, I; del Campo, IPM; Chamorro, AJ; Gimenez, RAFD; Madronero-Vuelta, AB; Ruiz-Munoz, M; Fonollosa-Pla, V; Simeon-Aznar, CP

Pulmonary hypertension in Spanish patients with systemic sclerosis. Data from the RESCLE registry

CLINICAL RHEUMATOLOGY, 2019;

FI:2,293; Q3

Lopez-Isac, E; Acosta-Herrera, M; Kerick, M; Assassi, S; Satpathy, AT; Granja, J; Mumbach, MR; Beretta, L; Simeon, CP; Carreira, P; Ortego-Centeno, N; Castellvi, I; Bossini-Castillo, L; Carmona, FD; Orozco, G; Hunzelmann, N; Distler, JHW; Franke, A; Lunardi, C; Moroncini, G; Gabrielli, A; de Vries-Bouwstra, J; Wijmenga, C; Koeleman, BPC; Nordin, A; Padyukov, L; Hoffmann-Vold, AM; Lie, B; Rios, R; Callejas, JL; Vargas-Hitos, JA; Garcia-Portales, R; Camps, MT; Fernandez-Nebro, A; Gonzalez-Escribano, MF; Garcia-Hernandez, FJ; Castillo, MJ; Aguirre, MA; Gomez-Gracia, I; Fernandez-Gutierrez, B; Rodriguez-Rodriguez, L; de la Pena, PG; Vicente, E; Andreu, JL; de Castro, MF; Lopez-Longo, FJ; Martinez, L; Fonollosa, V; Guillen, A; Espinosa, G; Tolosa, C; Pros, A; Rodriguez-Carballeira, M; Narvaez, FJ; Rubio-Rivas, M; Ortiz-Santamaria, V; Madronero, AB; Gonzalez-Gay, MA; Diaz, B; Trapiella, L; Sousa, A; Egurbide, MV; Fanlo-Mateo, P; Saez-Comet, L; Diaz, F; Hernandez, V; Beltran, E; Roman-Ivorra, JA; Grau, E; Alegre-Sancho, JJ; Freire, M; Blanco-Garcia, FJ; Oreiro, N; Witte, T; Kreuter, A; Riemekasten, G; Airo, P; Magro, C; Voskuyl, AE; Vonk, MC; Hesselstrand, R; Proudman, S; Stevens, W; Nikpour, M; Zochling, J; Sahhar, J; Roddy, J; Nash, P; Tymms, K; Rischmueller, M; Lester, S; Vyse, T; Herrick, AL; Worthington, J; Denton, CP; Allanore, Y; Brown, MA; Radstake, TRDJ; Fonseca, C; Chang, HY; Mayes, MD; Martin, J

GWAS for systemic sclerosis identifies multiple risk loci and highlights fibrotic and vasculopathy pathways

NATURE COMMUNICATIONS, 2019;

FI:11,878; D1

Gavilan-Carrera, B; da Silva, JG; Vargas-Hitos, JA; Sabio, JM; Morillas-de-Laguno, P; Rios-Fernandez, R; Delgado-Fernandez, M; Soriano-Maldonado, A

Association of physical fitness components and health-related quality of life in women with systemic lupus erythematosus with mild disease activity

PLOS ONE, 2019;

FI:2,776; Q2

Prados-Moreno, S; Sabio, JM; Perez-Marmol, JM; Navarrete-Navarrete, N; Peralta-Ramirez, MI

Adherence to treatment in patients with systemic lupus erythematosus

MEDICINA CLINICA, 2018;

FI:1,168; Q3

Garcia-Silva, J; Navarrete, NN; Rodriguez, AR; Peralta-Ramirez, MI; Garcia, JDM; Caballo, VE

Stress, anger and Mediterranean diet as predictors of metabolic syndrome

MEDICINA CLINICA, 2018;

FI:1,168; Q3

Manzano-Gamero, V; Pardo-Cabello, AJ; Vargas-Hitos, JA; Zamora-Pasadas, M; Navarrete-Navarrete, N; Sabio, JM; Jaimez-Gamiz, L; Rios-Fernandez, R; Ortego-Centeno, N; Ayala-Gutierrez, MM; de Ramon, E; Colodro-Ruiz, A; Mico-Giner, L; Castillo-Palma, MJ; Robles-Marhuenda, A; Luna-Del Castillo, JD; Jimenez-Alonso, J

Effect of ethnicity on clinical presentation and risk of antiphospholipid syndrome in Roma and Caucasian patients with systemic lupus erythematosus: a multicenter cross-sectional study

INTERNATIONAL JOURNAL OF RHEUMATIC DISEASES, 2018;

FI:2,423; Q3

Garcia-Silva, J; Peralta-Ramirez, MI; Navarrete, NN; Silva-Silva, D; Caballo, VE

Validity and reliability of the self-efficacy to regulate exercise scale in patients with metabolic syndrome

REVISTA ESPANOLA DE SALUD PUBLICA, 2018;

FI:0,635; Q4

Peralta-Ramirez, MI; Perez-Marmol, JM; Castaneda-Cabestany, M; Santos-Ruiz, AM; Montero-Lopez, E; Callejas-Rubio, JL; Navarrete-Navarrete, N; Fernandez-Sanchez, JC; Jimenez-Alonso, JF; Ortego-Centeno, N; Sabio, JM; Garcia-Morales, M

Association between perceived level of stress, clinical characteristics and psychopathological symptoms in women with systemic lupus erythematosus

CLINICAL AND EXPERIMENTAL RHEUMATOLOGY, 2018;

FI:3,201; Q2

Moraleda, V; Prados, G; Martinez, MP; Sanchez, AI; Sabio, JM; Miro, E

Sleep quality, clinical and psychological manifestations in women with systemic lupus erythematosus

INTERNATIONAL JOURNAL OF RHEUMATIC DISEASES, 2017;

FI:2,624; Q3

Rubio-Rivas, M; Simeon-Aznar, CP; Velasco, C; Mari-Alfonso, B; Espinosa, G; Corbella, X; Colunga-Arguelles, D; Egurbide-Arberas, MV; Ortego-Centeno, N; Vargas-Hitos, JA; Freire, M; Rios-Blanco, JJ; Trapiella-Martinez, L; Rodriguez-Carballeira, M; Fonollosa-Pla, V

Changes in the pattern of death of 987 patients with systemic sclerosis from 1990 to 2009 from the nationwide Spanish Scleroderma Registry (RESCLE)

CLINICAL AND EXPERIMENTAL RHEUMATOLOGY, 2017;

FI:2,634; Q3

Toral, M; Jimenez, R; Romero, M; Robles-Vera, I; Sanchez, M; Salaices, M; Sabio, JM; Duarte, J

Role of endoplasmic reticulum stress in the protective effects of PPAR beta/delta activation on endothelial dysfunction induced by plasma from patients with lupus

ARTHRITIS RESEARCH & THERAPY, 2017;

FI:4,121; Q1

Vargas-Hitos, JA; Fernandez-Munoz, J; Caba-Molina, M; Jimenez-Alonso, J

An Unusual Cause of Adult Respiratory Distress

ARCHIVOS DE BRONCONEUMOLOGIA, 2017;

FI:2,979; Q2

Sabio, JM; Rivero-Rodriguez, M; Vargas-Hitos, JA

Demographic and Clinical Characteristics Associated with Central Nervous System Hemorrhage in Patients with Eosinophilic Granulomatosis with Polyangiitis: A Case Report and Review of the Literature

JOURNAL OF RHEUMATOLOGY, 2017;

FI:3,15; Q2

Vargas-Hitos, JA; Sabio, JM; Navarrete-Navarrete, N; Arenas-Miras, MD; Zamora-Pasadas, M; Jimenez-Alonso, J

Cat scratch disease in an immunosuppressed patient with systemic lupus erythematosus

LUPUS, 2016;

FI:2,118; Q3

Montero-Lopez, E; Santos-Ruiz, A; Navarrete-Navarrete, N; Ortego-Centeno, N; Perez-Garcia, M; Peralta-Ramirez, MI

The effects of corticosteroids on cognitive flexibility and decision-making in women with lupus

LUPUS, 2016;

FI:2,118; Q3

Tolosa-Vilella, C; Morera-Morales, ML; Simeon-Aznar, CP; Mari-Alfonso, B; Colunga-Arguelles, D; Rubio, JLC; Rubio-Rivas, M; Freire-Dapena, M; Guillen-del Castillo, A; Iniesta-Arandia, N; Castillo-Palma, MJ; Egurbide-Arberas, M; Trapiellla-Martinez, L; Vargas-Hitos, JA; Todoli-Parra, JA; Rodriguez-Carballeira, M; Marin-Ballve, A; Pla-Salas, X; Rios-Blanco, JJ; Fonollosa-Pla, V

Digital ulcers and cutaneous subsets of systemic sclerosis: Clinical, immunological, nailfold capillaroscopy, and survival differences in the Spanish RESCLE Registry

SEMINARS IN ARTHRITIS AND RHEUMATISM, 2016;

FI:3,946; Q2

Ruiz-Irastorza, G; Garcia, M; Espinosa, G; Cabezas-Rodriguez, I; Mitjavila, F; Gonzalez-Leon, R; Sopena, B; Perales, I; Pinilla, B; Rodriguez-Carballeira, M; Lopez-Dupla, JM; Callejas, JL; Castro, A; Tolosa, C; Sanchez-Garcia, ME; Perez-Conesa, M; Navarrete-Navarrete, N; Rodriguez, AP; Herranz, MT; Pallares, L

Patterns of drug therapy in newly diagnosed Spanish patients with systemic lupus erythematosus

CLINICAL AND EXPERIMENTAL RHEUMATOLOGY, 2016;

FI:2,495; Q2

Soriano-Maldonado, A; Vargas-Hitos, JA; Sabio, JM

Cardiovascular training vs. resistance training for improving quality of life and physical function in patients with systemic lupus erythematosus: a randomized controlled trial: comments on the article by Abrahao et al

SCANDINAVIAN JOURNAL OF RHEUMATOLOGY, 2016;

FI:2,307; Q3

Sabio, JM; Vargas-Hitos, JA; Martinez-Bordonado, J; Navarrete-Navarrete, N; Diaz-Chamorro, A; Olvera-Porcel, C; Zamora, M; Jimenez-Alonso, J

Association between low 25-hydroxyvitamin D, insulin resistance and arterial stiffness in nondiabetic women with systemic lupus erythematosus

LUPUS, 2015;

FI:2,197; Q3

Serrano-Martinez, JL; Gil-Anguita, C; Vargas-Hitos, JA; Carretero-Garcia, S

Constitutional syndrome secondary to left atrial myxonna

REVISTA CLINICA ESPANOLA, 2015;

FI:1,063; Q3

Serrano-Martinez, JL; Zamora-Pasadas, M; Redondo-Orts, M

Paraneoplastic cerebellar degeneration associated with small cell neuroendocrine mediastinal carcinoma

ARCHIVOS DE BRONCONEUMOLOGIA, 2015;

FI:1,823; Q3

Saez-Comet, L; Simeon-Aznar, CP; Perez-Conesa, M; Vallejo-Rodriguez, C; Tolosa-Vilella, C; Iniesta-Arandia, N; Colunga-Arguelles, D; Egurbide-Arberas, MV; Ortego-Centeno, N; Vargas-Hitos, JA; Freire-Dapena, M; Rubio-Rivas, M; Rios-Blanco, JJ; Trapiella-Martinez, L; Fonollosa-Pla, V

Applying the ACR/EULAR Systemic Sclerosis Classification Criteria to the Spanish Scleroderma Registry Cohort

JOURNAL OF RHEUMATOLOGY, 2015;

FI:3,187; Q2

Ochoa, E; Martin, JE; Assassi, S; Beretta, L; Carreira, P; Guillen, A; Simeon, CP; Koumakis, E; Dieude, P; Allanore, Y; Garcia-Hernandez, FJ; Espinosa, G; Castellvi, I; Trapiella, JL; Rodriguez, L; Gonzalez-Gay, MA; Egurbide, MV; Saez, L; Callejas-Rubio, JL; Vargas-Hitos, JA; Hunzelmann, N; Riemekasten, G; Witte, T; Distler, JHW; Kreuter, A; Lunardi, C; Santaniello, A; Tan, FK; Shiels, PG; Herrick, A; Worthington, J; Vonk, MC; Koeleman, BP; Radstake, TRDJ; Mayes, MD; Martin, J

Confirmation of CCR6 as a risk factor for anti-topoisomerase I antibodies in systemic sclerosis

CLINICAL AND EXPERIMENTAL RHEUMATOLOGY, 2015;

FI:2,724; Q2

Efectos de Un Programa de Ejercicio Físico Sobre la Arteriosclerosis Subclínica y la Inflamación de Pacientes Con Lupus Eritematoso Sistémico

Financiador: CONSEJERÍA DE SALUD

Número de expediente: PI-0525-2016

Tiempo de ejecución: 01/01/2017 - 31/12/2017

IP: JOSE ANTONIO VARGAS HITOS

Estudio aleatorizado, doble ciego, controlado con placebo, de la seguridad y la eficacia de diferentes dosis y pautas posologicas de evinacumab en pacientes con hipercolesterolemia cronica a pesar del tratamiento hipolipidemiante maximo tolerado

Financiador: REGENERON PHARMACEUTICALS, INC

Tipo de prueba: ENSAYO CLINICO COMERCIAL

Tiempo de ejecución: 15/05/2018 - 30/12/2020

IP: JUAN DIEGO MEDIAVILLA GARCIA

Líneas de investigación

JUAN DIEGO MEDIAVILLA GARCIA

NURIA NAVARRETE NAVARRETE

GERMAN PRADOS GARCIA

ANA ROSALES MARTIN

JOSE MARIO SABIO SANCHEZ

JOSE ANTONIO VARGAS HITOS

MONICA ZAMORA PASADAS

ANTONIO DIAZ CHAMORRO

LAURA JAIMEZ GAMIZ

Investigación