MP03-Lupus

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Nuestro grupo está centrado en el Riesgo Cardiovascular en las Enfermedades Autoinmunes Sistémicas.

Líneas de investigación

Ejercicio físico y LES
Riesgo Cardiovascular en otras enfermedades autoinmunes sistémicas distintas a LES
Riesgo cardiovascular en lupus eritematoso sistémico

JUAN DIEGO MEDIAVILLA GARCIA

NURIA NAVARRETE NAVARRETE

GERMAN PRADOS GARCIA

ANA ROSALES MARTIN

JOSE MARIO SABIO SANCHEZ

JOSE ANTONIO VARGAS HITOS

MONICA ZAMORA PASADAS

ANTONIO DIAZ CHAMORRO

LAURA JAIMEZ GAMIZ

Garcia-Hernandez, FJ; Castillo-Palma, MJ; Tolosa-Vilella, C; Guillen-del Castillo, A; Rubio-Rivas, M; Freire, M; Vargas-Hitos, JA; Todoli-Parra, JA; Rodriguez-Carballeira, M; Espinosa-Garriga, G; Colunga-Arguelles, D; Ortego-Centeno, N; Trapiella-Martinez, L; Rodero-Roldan, MM; Pla-Salas, X; Perales-Fraile, I; del Campo, IPM; Chamorro, AJ; Gimenez, RAFD; Madronero-Vuelta, AB; Ruiz-Munoz, M; Fonollosa-Pla, V; Simeon-Aznar, CP

Pulmonary hypertension in Spanish patients with systemic sclerosis. Data from the RESCLE registry

CLINICAL RHEUMATOLOGY, 2019;

FI:2,293; Q3

da Silva, JG; Peralta-Ramirez, MI; Navarrete-Navarrete, N; Silva-Silva, D; Wendt, GW; Caballo, VE

Psychometric properties of Self-Efficacy to Regulate Eating Habits (SEREH) scale

REVISTA ESPANOLA DE NUTRICION HUMANA Y DIETETICA, 2019;

Sola-Rodriguez, S; Gavilan-Carrera, B; Vargas-Hitos, JA; Sabio, JM; Morillas-de-Laguno, P; Soriano-Maldonado, A

Physical Fitness and Body Composition in Women with Systemic Lupus Erythematosus

MEDICINA-LITHUANIA, 2019;

Lopez-Isac, E; Acosta-Herrera, M; Kerick, M; Assassi, S; Satpathy, AT; Granja, J; Mumbach, MR; Beretta, L; Simeon, CP; Carreira, P; Ortego-Centeno, N; Castellvi, I; Bossini-Castillo, L; Carmona, FD; Orozco, G; Hunzelmann, N; Distler, JHW; Franke, A; Lunardi, C; Moroncini, G; Gabrielli, A; de Vries-Bouwstra, J; Wijmenga, C; Koeleman, BPC; Nordin, A; Padyukov, L; Hoffmann-Vold, AM; Lie, B; Rios, R; Callejas, JL; Vargas-Hitos, JA; Garcia-Portales, R; Camps, MT; Fernandez-Nebro, A; Gonzalez-Escribano, MF; Garcia-Hernandez, FJ; Castillo, MJ; Aguirre, MA; Gomez-Gracia, I; Fernandez-Gutierrez, B; Rodriguez-Rodriguez, L; de la Pena, PG; Vicente, E; Andreu, JL; de Castro, MF; Lopez-Longo, FJ; Martinez, L; Fonollosa, V; Guillen, A; Espinosa, G; Tolosa, C; Pros, A; Rodriguez-Carballeira, M; Narvaez, FJ; Rubio-Rivas, M; Ortiz-Santamaria, V; Madronero, AB; Gonzalez-Gay, MA; Diaz, B; Trapiella, L; Sousa, A; Egurbide, MV; Fanlo-Mateo, P; Saez-Comet, L; Diaz, F; Hernandez, V; Beltran, E; Roman-Ivorra, JA; Grau, E; Alegre-Sancho, JJ; Freire, M; Blanco-Garcia, FJ; Oreiro, N; Witte, T; Kreuter, A; Riemekasten, G; Airo, P; Magro, C; Voskuyl, AE; Vonk, MC; Hesselstrand, R; Proudman, S; Stevens, W; Nikpour, M; Zochling, J; Sahhar, J; Roddy, J; Nash, P; Tymms, K; Rischmueller, M; Lester, S; Vyse, T; Herrick, AL; Worthington, J; Denton, CP; Allanore, Y; Brown, MA; Radstake, TRDJ; Fonseca, C; Chang, HY; Mayes, MD; Martin, J

GWAS for systemic sclerosis identifies multiple risk loci and highlights fibrotic and vasculopathy pathways

NATURE COMMUNICATIONS, 2019;

FI:11,878; D1

Gavilan-Carrera, B; da Silva, JG; Vargas-Hitos, JA; Sabio, JM; Morillas-de-Laguno, P; Rios-Fernandez, R; Delgado-Fernandez, M; Soriano-Maldonado, A

Association of physical fitness components and health-related quality of life in women with systemic lupus erythematosus with mild disease activity

PLOS ONE, 2019;

FI:2,776; Q2

Prados-Moreno, S; Sabio, JM; Perez-Marmol, JM; Navarrete-Navarrete, N; Peralta-Ramirez, MI

Adherence to treatment in patients with systemic lupus erythematosus

MEDICINA CLINICA, 2018;

FI:1,168; Q3

Garcia-Silva, J; Navarrete, NN; Rodriguez, AR; Peralta-Ramirez, MI; Garcia, JDM; Caballo, VE

Stress, anger and Mediterranean diet as predictors of metabolic syndrome

MEDICINA CLINICA, 2018;

FI:1,168; Q3

Manzano-Gamero, V; Pardo-Cabello, AJ; Vargas-Hitos, JA; Zamora-Pasadas, M; Navarrete-Navarrete, N; Sabio, JM; Jaimez-Gamiz, L; Rios-Fernandez, R; Ortego-Centeno, N; Ayala-Gutierrez, MM; de Ramon, E; Colodro-Ruiz, A; Mico-Giner, L; Castillo-Palma, MJ; Robles-Marhuenda, A; Luna-Del Castillo, JD; Jimenez-Alonso, J

Effect of ethnicity on clinical presentation and risk of antiphospholipid syndrome in Roma and Caucasian patients with systemic lupus erythematosus: a multicenter cross-sectional study

INTERNATIONAL JOURNAL OF RHEUMATIC DISEASES, 2018;

FI:2,423; Q3

Garcia-Silva, J; Peralta-Ramirez, MI; Navarrete, NN; Silva-Silva, D; Caballo, VE

Validity and reliability of the self-efficacy to regulate exercise scale in patients with metabolic syndrome

REVISTA ESPANOLA DE SALUD PUBLICA, 2018;

FI:0,635; Q4

Soriano-Maldonado, A; Morillas-de-Laguno, P; Sabio, JM; Gavilan-Carrera, B; Rosales-Castillo, A; Montalban-Mendez, C; Saez-Uran, LM; Callejas-Rubio, JL; Vargas-Hitos, JA

Effects of 12-week Aerobic Exercise on Arterial Stiffness, Inflammation, and Cardiorespiratory Fitness in Women with Systemic LUPUS Erythematosus: Non-Randomized Controlled Trial

JOURNAL OF CLINICAL MEDICINE, 2018;

FI:5,583; D1

Moraleda, V; Prados, G; Martinez, MP; Sanchez, AI; Sabio, JM; Miro, E

Sleep quality, clinical and psychological manifestations in women with systemic lupus erythematosus

INTERNATIONAL JOURNAL OF RHEUMATIC DISEASES, 2017;

FI:2,624; Q3

Rubio-Rivas, M; Simeon-Aznar, CP; Velasco, C; Mari-Alfonso, B; Espinosa, G; Corbella, X; Colunga-Arguelles, D; Egurbide-Arberas, MV; Ortego-Centeno, N; Vargas-Hitos, JA; Freire, M; Rios-Blanco, JJ; Trapiella-Martinez, L; Rodriguez-Carballeira, M; Fonollosa-Pla, V

Changes in the pattern of death of 987 patients with systemic sclerosis from 1990 to 2009 from the nationwide Spanish Scleroderma Registry (RESCLE)

CLINICAL AND EXPERIMENTAL RHEUMATOLOGY, 2017;

FI:2,634; Q3

Trapiella-Martinez, L; Diaz-Lopez, JB; Caminal-Montero, L; Tolosa-Vilella, C; Castillo, AGD; Colunga-Arguelles, D; Rubio-Rivas, M; Iniesta-Arandia, N; Castillo-Palma, MJ; Saez-Comet, L; Egurbide-Arberas, MV; Ortego-Centeno, N; Freire, M; Vargas-Hitos, JA; Rios-Blanco, JJ; Todoli-Parra, JA; Rodriguez-Carballeira, M; Marin-Ballve, A; Chamorro-Fernandez, AJ; Pla-Salas, X; Madronero-Vuelta, AB; Ruiz-Munoz, M; Fonollosa-Pla, V; Simeon-Aznar, CP

Very early and early systemic sclerosis in the Spanish scleroderma Registry (RESCLE) cohort

AUTOIMMUNITY REVIEWS, 2017;

FI:8,961; D1

Toral, M; Jimenez, R; Romero, M; Robles-Vera, I; Sanchez, M; Salaices, M; Sabio, JM; Duarte, J

Role of endoplasmic reticulum stress in the protective effects of PPAR beta/delta activation on endothelial dysfunction induced by plasma from patients with lupus

ARTHRITIS RESEARCH & THERAPY, 2017;

FI:4,121; Q1

Vargas-Hitos, JA; Fernandez-Munoz, J; Caba-Molina, M; Jimenez-Alonso, J

An Unusual Cause of Adult Respiratory Distress

ARCHIVOS DE BRONCONEUMOLOGIA, 2017;

FI:2,979; Q2

Vargas-Hitos, JA; Sabio, JM; Navarrete-Navarrete, N; Arenas-Miras, MD; Zamora-Pasadas, M; Jimenez-Alonso, J

Cat scratch disease in an immunosuppressed patient with systemic lupus erythematosus

LUPUS, 2016;

FI:2,118; Q3

Montero-Lopez, E; Santos-Ruiz, A; Navarrete-Navarrete, N; Ortego-Centeno, N; Perez-Garcia, M; Peralta-Ramirez, MI

The effects of corticosteroids on cognitive flexibility and decision-making in women with lupus

LUPUS, 2016;

FI:2,118; Q3

Vargas-Hitos, JA; Sabio, JM; Navarrete-Navarrete, N; Zamora-Pasadas, M; Jimenez-Alonso, J

Severe digital necrosis as the clinical onset of antiphospholipid syndrome

INTERNAL AND EMERGENCY MEDICINE, 2016;

FI:2,34; Q1

Rivera-Lopez, R; Jimenez-Jaimez, J; Sabio, JM; Zamora-Pasadas, M; Vargas-Hitos, JA; Martinez-Bordonado, J; Navarrete-Navarrete, N; Fernandez, RR; Sanchez-Cantalejo, E; Jimenez-Alonso, J

Relationship between QT Interval Length and Arterial Stiffness in Systemic Lupus Erythematosus (SLE): A Cross-Sectional Case-Control Study

PLOS ONE, 2016;

FI:3,057; Q1

Vargas-Hitos, JA; Roa-Chamorro, R; Sabio, JM; Javier-Martinez, R; Martin-Castro, A; Jimenez-Alonso, J

Leishmaniasis, lupus nephritis and immunosuppressive therapy

QJM-AN INTERNATIONAL JOURNAL OF MEDICINE, 2016;

FI:2,824; Q1

Sabio, JM; Vargas-Hitos, JA; Martinez-Bordonado, J; Navarrete-Navarrete, N; Diaz-Chamorro, A; Olvera-Porcel, C; Zamora, M; Jimenez-Alonso, J

Association between low 25-hydroxyvitamin D, insulin resistance and arterial stiffness in nondiabetic women with systemic lupus erythematosus

LUPUS, 2015;

FI:2,197; Q3

Serrano-Martinez, JL; Gil-Anguita, C; Vargas-Hitos, JA; Carretero-Garcia, S

Constitutional syndrome secondary to left atrial myxonna

REVISTA CLINICA ESPANOLA, 2015;

FI:1,063; Q3

Serrano-Martinez, JL; Zamora-Pasadas, M; Redondo-Orts, M

Paraneoplastic cerebellar degeneration associated with small cell neuroendocrine mediastinal carcinoma

ARCHIVOS DE BRONCONEUMOLOGIA, 2015;

FI:1,823; Q3

Simeon-Aznar, CP; Fonollosa-Pla, V; Tolosa-Vilella, C; Espinosa-Garriga, G; Campillo-Grau, M; Ramos-Casals, M; Garcia-Hernandez, FJ; Castillo-Palma, MJ; Sanchez-Roman, J; Callejas-Rubio, JL; Ortego-Centeno, N; Egurbide-Arberas, MV; Trapiellla-Martinez, L; Caminal-Montero, L; Saez-Comet, L; Velilla-Marco, J; Camps-Garcia, MT; de Ramon-Garrido, E; Esteban-Marcos, EM; Pallares-Ferreres, L; Navarrete-Navarrete, N; Vargas-Hitos, JA; de la Torre, RG; Salvador-Cervello, G; Rios-Blanco, JJ; Vilardell-Tarres, M

Registry of the Spanish Network for Systemic Sclerosis Survival, Prognostic Factors, and Causes of Death

MEDICINE, 2015;

FI:5,723; D1

Sabio, JM; Sanchez-Berna, I; Martinez-Bordonado, J; Vargas-Hitos, JA; Navarrete-Navarrete, N; Ruiz, ME; Jimenez-Alonso, J

Prevalence of and Factors Associated With Increased Arterial Stiffness in Patients With Primary Sjogren’s Syndrome

ARTHRITIS CARE & RESEARCH, 2015;

FI:4,713; Q1

Efectos de Un Programa de Ejercicio Físico Sobre la Arteriosclerosis Subclínica y la Inflamación de Pacientes Con Lupus Eritematoso Sistémico

Financiador: CONSEJERÍA DE SALUD

Número de expediente: PI-0525-2016

Tiempo de ejecución: 01/01/2017 - 31/12/2017

IP: JOSE ANTONIO VARGAS HITOS

Estudio aleatorizado, doble ciego, controlado con placebo, de la seguridad y la eficacia de diferentes dosis y pautas posologicas de evinacumab en pacientes con hipercolesterolemia cronica a pesar del tratamiento hipolipidemiante maximo tolerado

Financiador: REGENERON PHARMACEUTICALS, INC

Tipo de prueba: ENSAYO CLINICO COMERCIAL

Tiempo de ejecución: 15/05/2018 - 30/12/2020

IP: JUAN DIEGO MEDIAVILLA GARCIA

Líneas de investigación

JUAN DIEGO MEDIAVILLA GARCIA

NURIA NAVARRETE NAVARRETE

GERMAN PRADOS GARCIA

ANA ROSALES MARTIN

JOSE MARIO SABIO SANCHEZ

JOSE ANTONIO VARGAS HITOS

MONICA ZAMORA PASADAS

ANTONIO DIAZ CHAMORRO

LAURA JAIMEZ GAMIZ

Investigación