MP07-Bases Fisiopatologia y Terapeutica Medica

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Grupo de investigación dedicado a profundizar en el conocimiento de las enfermedades autoinmunes sistémicas desde el punto de vista epidemiológico, clínico, genético y de inmunología básica. Además, trabaja en el estudio de los factores de riesgo asociados con el desarrollo de osteoporosis esteroidea, así como de su prevención y tratamiento.

Palabras clave

Enfermedades Autoinmunes, Lupus, Esclerodermia, Vasculitis Sistémicas, Uveitis, Osteoporosis Y Glucocorticoídes.

JOSE LUIS CALLEJAS RUBIO

MARIA CORREA RODRIGUEZ

MARIA CONCEPCION FERNANDEZ ROLDAN

ANA MARIA MARQUEZ ORTIZ

NORBERTO ORTEGO CENTENO

GABRIELA POCOVI

RAQUEL RIOS FERNANDEZ

BLANCA Mª RUEDA MEDINA

Rios-Fernandez, R; Callejas-Rubio, JL; Ortego-Centeno, N

Effectiveness of Quinacrine (Mepacrine) in Photosensitive Autoimmune Diseases, Lupus Erythematosus, and Dermatomyositis: Report on 38 Cases and Literature Review

ARCHIVES OF RHEUMATOLOGY, 2019;

FI:0,274; Q4

Pocovi-Gerardino, G; Correa-Rodriguez, M; Rubio, JLC; Fernandez, RR; Ortego-Centeno, N; Rueda-Medina, B

Diet Quality and High-Sensitivity C-Reactive Protein in Patients With Systemic Lupus Erythematosus

BIOLOGICAL RESEARCH FOR NURSING, 2019;

FI:1,513; Q2

Gavilan-Carrera, B; da Silva, JG; Vargas-Hitos, JA; Sabio, JM; Morillas-de-Laguno, P; Rios-Fernandez, R; Delgado-Fernandez, M; Soriano-Maldonado, A

Association of physical fitness components and health-related quality of life in women with systemic lupus erythematosus with mild disease activity

PLOS ONE, 2019;

FI:2,776; Q2

Castano-Nunez, A; Montes-Cano, MA; Garcia-Lozano, JR; Ortego-Centeno, N; Garcia-Hernandez, FJ; Espinosa, G; Grana-Gil, G; Sanchez-Burson, J; Julia, MR; Solans, R; Blanco, R; Barnosi-Marin, AC; de la Torre, RG; Fanlo, P; Rodriguez-Carballeira, M; Rodriguez-Rodriguez, L; Camps, T; Castaneda, S; Alegre-Sancho, JJ; Martin, J; Gonzalez-Escribano, MF

Association of Functional Polymorphisms of KIR3DL1/DS1 With Behcet’s Disease

FRONTIERS IN IMMUNOLOGY, 2019;

FI:4,716; Q2

Ruiz-Limon, P; Ortega-Castro, R; Barbarroja, N; Perez-Sanchez, C; Jamin, C; Patino-Trives, AM; Luque-Tevar, M; Ibanez-Costa, A; Perez-Sanchez, L; de la Rosa, IA; Abalos-Aguilera, M; Jimenez-Gomez, Y; Calvo-Gutierrez, J; Font, P; Escudero-Contreras, A; Alarcon-Riquelme, ME; Collantes-Estevez, E; Lopez-Pedrera, C; Maranon, C; Le Lann, L; Varela, N; Muchmore, B; Dufour, A; Alvarez; Chizzolini, CCM; De Langhe,; Gerl, V; De Groof, A; Ducreux, J; Trombetta, E; Li, T; Alvarez-Errico, D; Rao, S; Pers, JO; Beretta, L; AguilarQuesada, R; Aguirre-Zamorano, MA; Rubio, JLC; Castro-Villegas, MC; Cervera, R; Chizzolini, C; Collantes, E; Cornec, D; De Langhe, E; Devauchelle-Pensec, V; Espinosa, G; Roldan, MCF; Anjos, TG; Hiepe, F; Moleon, IJ; Jousse-Joulin, S; Lauwerys, B; Lopez-Berrio, A; Lories, R; Marovac, J; Meroni, PL; Miranda, B; Navarro-Linares, H; Ortega-Castro, R; Ortego, N; Pers, JO; Garrido, ER; Raya, E; Fernandez, RR; Rodriguez-Pinto, I; Saraux, A

Molecular Characterization of Monocyte Subsets Reveals Specific and Distinctive Molecular Signatures Associated With Cardiovascular Disease in Rheumatoid Arthritis

FRONTIERS IN IMMUNOLOGY, 2019;

FI:4,716; Q2

Ugarte, A; Porta, S; Rios, R; Martinez-Zapico, A; Ortego-Centeno, N; Agesta, N; Ruiz-Irastorza, G

Combined mepacrine-hydroxychloroquine treatment in patients with systemic lupus erythematosus and refractory cutaneous and articular activity

LUPUS, 2018;

FI:2,969; Q3

Sanchez-Cano, D; Ortego-Centeno, N; Callejas, JL; Pla, VF; Rios-Fernandez, R; Tolosa-Vilella, C; Espinosa-Garriga, G; Colunga-Arguelles, D; Egurbide-Arberas, MV; Rubio-Rivas, M; Freire, M; Rios-Blanco, JJ; Trapiella-Martinez, L; Rodriguez-Carballeira, M; Marin-Ballve, A; Pla-Salas, X; Simeon-Aznar, CP

Interstitial lung disease in systemic sclerosis: data from the spanish scleroderma study group

RHEUMATOLOGY INTERNATIONAL, 2018;

FI:1,952; Q4

Pocovi-Gerardino, G; Correa-Rodriguez, M; Callejas-Rubio, JL; Rios-Fernandez, R; Ortego-Centeno, N; Rueda-Medina, B

Dietary intake and nutritional status in patients with systemic lupus erythematosus

ENDOCRINOLOGIA DIABETES Y NUTRICION, 2018;

Porras, C; Sanchez-Espin, G; Such, M; Sanchez-Ramos, J; Bautista-Paves, A; Martin-Dela Fuente, P; Ruiz, J; Ortego-Centeno, N; Rodriguez-Bailon, I; Melero, JM

Aortitis as a Rare Cause of Aortic Aneurysm and Valve Regurgitation: Is Repair Precluded?

CASE REPORTS IN CARDIOLOGY, 2018;

Correa-Rodriguez, M; Valle, JSR; De la Fuente-Vilchez, AM; Rueda-Medina, B

Analysis of lifestyle and bone mineralization in a population of Spanish young adults

COLOMBIA MEDICA, 2018;

FI:0,982; Q3

Garcia, AG; de la Pena, JLP; Centeno, NO

Autoinflammatory diseases in adults. Clinical characteristics and prognostic implications

REVISTA CLINICA ESPANOLA, 2017;

FI:0,971; Q3

Moreno-Higueras, M; Callejas-Rubio, JL; Gallo-Padilla, L

Dress syndrome and bilateral panuveitis caused by strontium ranelate

MEDICINA CLINICA, 2017;

FI:1,125; Q3

Freire, M; Rivera, A; Sopena, B; Vilella, CT; Guillen-Del Castillo, A; Arguelles, DC; Rubio, JLC; Rivas, MR; Martinez, LT; Parra, JAT; Carballeira, MR; Arandia, NI; Hernandez, FJG; Arberas, MVE; Comet, LS; Hitos, JAV; Blanco, JJR; Ballve, AM; Salas, XP; Vuelta, ABM; Munoz, MR; Pla, VF; Aznar, CPS

Clinical and epidemiological differences between men and women with systemic sclerosis: a study in a Spanish systemic sclerosis cohort and literature review

CLINICAL AND EXPERIMENTAL RHEUMATOLOGY, 2017;

FI:2,634; Q3

Arandia, NI; Simeon-Aznar, CP; del Castillo, AG; Arguelles, DC; Rubio-Rivas, M; Martinez, LT; Hernandez, FJG; Comet, LS; Arberas, MVE; Ortego-Centeno, N; Freire, M; Alfonso, BM; Hitos, JAV; Blanco, JJR; Parra, JAT; Rodriguez-Carballeira, M; Ballve, AM; Fernandez, AJC; Salas, XP; Vuelta, ABM; Munoz, MR; Pla, VF; Espinosa, G

Influence of antibody profile in clinical features and prognosis in a cohort of Spanish patients with systemic sclerosis

CLINICAL AND EXPERIMENTAL RHEUMATOLOGY, 2017;

FI:2,634; Q3

Rubio-Rivas, M; Simeon-Aznar, CP; Velasco, C; Mari-Alfonso, B; Espinosa, G; Corbella, X; Colunga-Arguelles, D; Egurbide-Arberas, MV; Ortego-Centeno, N; Vargas-Hitos, JA; Freire, M; Rios-Blanco, JJ; Trapiella-Martinez, L; Rodriguez-Carballeira, M; Fonollosa-Pla, V

Changes in the pattern of death of 987 patients with systemic sclerosis from 1990 to 2009 from the nationwide Spanish Scleroderma Registry (RESCLE)

CLINICAL AND EXPERIMENTAL RHEUMATOLOGY, 2017;

FI:2,634; Q3

Lopez-Robles, C; Rios-Fernandez, R; Callejas-Rubio, JL; Moreno-Escobar, E; Ortego-Centeno, N

Low bone mass and carotid atherosclerosis in lupus erythematosus patients from Granada, a city in the south of Spain

LUPUS, 2016;

FI:2,118; Q3

Montero-Lopez, E; Santos-Ruiz, A; Navarrete-Navarrete, N; Ortego-Centeno, N; Perez-Garcia, M; Peralta-Ramirez, MI

The effects of corticosteroids on cognitive flexibility and decision-making in women with lupus

LUPUS, 2016;

FI:2,118; Q3

Rios-Fernandez, R; Callejas-Rubio, JL; Garcia-Rodriguez, S; Sancho, J; Zubiaur, M; Ortego-Centeno, N

Tocilizumab as an Adjuvant Therapy for Hemophagocytic Lymphohistiocytosis Associated With Visceral Leishmaniasis

AMERICAN JOURNAL OF THERAPEUTICS, 2016;

FI:1,132; Q4

Fernandez-Roldan, C; Genre, F; Lopez-Mejias, R; Ubilla, B; Mijares, V; Cano, DS; Robles, CL; Callejas-Rubio, JL; Fernandez, RR; Ruiz, ME; Gonzalez-Gay, MA; Centeno, NO

Sclerostin serum levels in patients with systemic autoimmune diseases

BONEKEY REPORTS, 2016;

Gonzalez-Moreno, J; Losada-Lopez, I; Gallego-Lezaun, C; Garcia-Gasalla, M; Bellvert, CG; Centeno, NO

Serosal involvement in IgG4-related disease: report of two cases and review of the literature

RHEUMATOLOGY INTERNATIONAL, 2016;

FI:1,702; Q3

Ortiz-Fernandez, L; Garcia-Lozano, JR; Montes-Cano, MA; Conde-Jaldon, M; Ortego-Centeno, N; Garcia-Hernandez, FJ; Espinosa, G; Grana-Gil, G; Sanchez-Burson, J; Blanco, R; Barnosi-Marin, AC; Solans, R; Fanlo, P; Rodriguez-Carballeira, M; Camps, T; Castaneda, S; Nunez-Roldan, A; Martin, J; Gonzalez-Escribano, MF

Variants of the IFI16 Gene Affecting the Levels of Expression of mRNA Are Associated with Susceptibility to Behcet Disease

JOURNAL OF RHEUMATOLOGY, 2015;

FI:3,187; Q2

Gonzalez-Moreno, J; Callejas-Rubio, JL; Rios-Fernandez, R; Ortego-Centeno, N

Antiphospholipid syndrome, antiphospholipid antibodies and solid organ transplantation

LUPUS, 2015;

FI:2,197; Q3

Gonzalez-Moreno, J; Ruiz-Ruigomez, M; Rubio, JLC; Fernandez, RR; Centeno, NO

Pyoderma gangrenosum and systemic lupus erythematosus: a report of five cases and review of the literature

LUPUS, 2015;

FI:2,197; Q3

Coin, MA; Vilar-Lopez, R; Peralta-Ramirez, I; Hidalgo-Ruzzante, N; Callejas-Rubio, JL; Ortego-Centeno, N; Perez-Garcia, M

The role of antiphospholipid autoantibodies in the cognitive deficits of patients with systemic lupus erythematosus

LUPUS, 2015;

FI:2,197; Q3

Lopez-Mejias, R; Genre, F; Perez, BS; Castaneda, S; Ortego-Centeno, N; Llorca, J; Ubilla, B; Remuzgo-Martinez, S; Mijares, V; Pina, T; Calvo-Rio, V; Marquez, A; Sala-Icardo, L; Miranda-Filloy, JA; Conde-Jaldon, M; Ortiz-Fernandez, L; Rubio, E; Luque, ML; Blanco-Madrigal, JM; Galindez-Aguirregoikoa, E; Gonzalez-Vela, MC; Ocejo-Vinyals, JG; Escribano, FG; Martin, J; Blanco, R; Gonzalez-Gay, MA

Association of HLA-DRB1*01 With IgA Vasculitis (Henoch-Schonlein)

ARTHRITIS & RHEUMATOLOGY, 2015;

Detección Precoz de Osteoporosis: Identificación de Factores Genéticos Implicados en la Mineralización Ósea en Adultos Jóvenes

Financiador: FUNDACION PUBLICA ANDALUZA PROGRESO Y SALUD

Número de expediente: PI-0414-2014

Tiempo de ejecución: 31/07/2015 - 01/08/2017

IP: BLANCA Mª RUEDA MEDINA

Identificación de Factores Genéticos Implicados en el Desarrollo de Úlceras Digitales en Pacientes de Esclerodermia Mediante Un Estudio de Asociación del Genoma Completo (Gwas)

Financiador: FUNDACION PUBLICA ANDALUZA PROGRESO Y SALUD

Número de expediente: PI-0390-2014

Tiempo de ejecución: 31/07/2015 - 01/08/2017

IP: ANA MARIA MARQUEZ ORTIZ

Lydimed: Lupus y Dieta Mediterránea

Financiador: CONSEJERÍA DE SALUD

Número de expediente: PI-0523-2016

Tiempo de ejecución: 01/01/2017 - 31/12/2019

IP: NORBERTO ORTEGO CENTENO

Identificación de Factores Genéticos de Riesgo Compartidos Entre Enfermedades Reumáticas Mediante Una Estrategia Meta-Immunochip

Financiador: CONSEJERÍA DE SALUD

Número de expediente: PI-0493-2016

Tiempo de ejecución: 01/01/2017 - 31/12/2019

IP: RAQUEL RIOS FERNANDEZ

Study of the molecular basis of giant cell arteritis by integrating genomic, transcriptomic and methylation data.

Financiador: INSTITUTO DE SALUD CARLOS III

Número de expediente: CP17/00008-P

Tiempo de ejecución: 01/01/2018 - 31/12/2020

IP: ANA MARIA MARQUEZ ORTIZ

Identificación de los mecanismos patogénicos implicados en el desarrollo de la arteritis de células gigantes mediante secuenciación del transcriptoma de células T individuales

Financiador: INSTITUTO DE SALUD CARLOS III

Número de expediente: PI18/00040

Tiempo de ejecución: 01/01/2019 - 31/12/2021

IP: ANA MARIA MARQUEZ ORTIZ

MP07-Bases Fisiopatologia y Terapeutica Medica

Palabras clave

JOSE LUIS CALLEJAS RUBIO

MARIA CORREA RODRIGUEZ

MARIA CONCEPCION FERNANDEZ ROLDAN

ANA MARIA MARQUEZ ORTIZ

NORBERTO ORTEGO CENTENO

GABRIELA POCOVI

RAQUEL RIOS FERNANDEZ

BLANCA Mª RUEDA MEDINA

Investigación