MP09-Neurofarmacologia del Dolor

Prevalence and risk factors associated with fatal adverse drug reactions among patients admitted at a Spanish teaching hospital

EUROPEAN JOURNAL OF INTERNAL MEDICINE, 2019;

FI:3,66; Q1

Modulation by Sigma-1 Receptor of Morphine Analgesia and Tolerance: Nociceptive Pain, Tactile Allodynia and Grip Strength Deficits During Joint Inflammation

FRONTIERS IN PHARMACOLOGY, 2019;

FI:3,845; Q1

Potential drug-drug interactions in deceased inpatients

INTERNAL AND EMERGENCY MEDICINE, 2019;

FI:2,335; Q2

Tetrahydro-3-benzazepines with fluorinated side chains as NMDA and sigma(1) receptor antagonists: Synthesis, receptor affinity, selectivity and antiallodynic activity

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019;

FI:4,833; D1

A novel nanoformulation of PLGA with high non-ionic surfactant content improves in vitro and in vivo PTX activity against lung cancer

PHARMACOLOGICAL RESEARCH, 2019;

FI:5,574; D1

Targeting immune-driven opioid analgesia by sigma-1 receptors: Opening the door to novel perspectives for the analgesic use of sigma-1 antagonists

PHARMACOLOGICAL RESEARCH, 2018;

FI:4,897; D1

(+)-Methyl (1R,2S)-2-{[4-(4-Chlorophenyl)-4-hydroxypiperidin-1-yl]methyl}-1-phenylcyclopropanecarboxylate [(+)-MR200] Derivatives as Potent and Selective Sigma Receptor Ligands: Stereochemistry and Pharmacological Properties

JOURNAL OF MEDICINAL CHEMISTRY, 2018;

FI:6,253; D1

Contilisant, a Tetratarget Small Molecule for Alzheimer’s Disease Therapy Combining Cholinesterase, Monoamine Oxidase Inhibition, and H3R Antagonism with S1R Agonism Profile

JOURNAL OF MEDICINAL CHEMISTRY, 2018;

FI:6,253; D1

Synthesis, Receptor Affinity, and Antiallodynic Activity of Spirocyclic sigma Receptor Ligands with Exocyclic Amino Moiety

JOURNAL OF MEDICINAL CHEMISTRY, 2018;

FI:6,253; D1

Mechanistic Differences in Neuropathic Pain Modalities Revealed by Correlating Behavior with Global Expression Profiling

CELL REPORTS, 2018;

FI:8,032; Q1

Inflammatory pain control by blocking oxidized phospholipid-mediated TRP channel activation

SCIENTIFIC REPORTS, 2017;

FI:4,259; Q1

Opioids and immunosupression in oncological postoperative patients

REVISTA DA ASSOCIACAO MEDICA BRASILEIRA, 2017;

FI:0,931; Q3

Grip strength in mice with joint inflammation: A rheumatology function test sensitive to pain and analgesia

NEUROPHARMACOLOGY, 2017;

FI:5,012; D1

Sigma-1 receptors control immune-driven peripheral opioid analgesia during inflammation in mice

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2017;

FI:9,661; D1

Paclitaxel-loaded hollow-poly(4-vinylpyridine) nanoparticles enhance drug chemotherapeutic efficacy in lung and breast cancer cell lines

NANO RESEARCH, 2017;

FI:7,354; D1

Sigma-1 Receptor Agonism Promotes Mechanical Allodynia After Priming the Nociceptive System with Capsaicin

SCIENTIFIC REPORTS, 2016;

FI:5,228; Q1

Low adherent cancer cell subpopulations are enriched in tumorigenic and metastatic epithelial-to-mesenchymal transition-induced cancer stem-like cells

SCIENTIFIC REPORTS, 2016;

FI:5,228; Q1

Distinguishing subgroups among mu-opioid receptor agonists using Na+,K+-ATPase as an effector mechanism

EUROPEAN JOURNAL OF PHARMACOLOGY, 2016;

FI:2,73; Q2

Analysis of food advertising to children on Spanish television: probing exposure to television marketing

ARCHIVES OF MEDICAL SCIENCE, 2016;

FI:1,812; Q2

Maternal, fetal and perinatal alterations associated with obesity, overweight and gestational diabetes: an observational cohort study (PREOBE)

BMC PUBLIC HEALTH, 2016;

FI:2,209; Q2

Trends in the dispensation of antidepressant drugs over the past decade (2000-2010) in Andalusia, Spain

SOCIAL PSYCHIATRY AND PSYCHIATRIC EPIDEMIOLOGY, 2015;

FI:2,537; Q2

Use of Very-Low-Dose Methadone and Haloperidol for Pain Control in Palliative Care Patients: Are the Sigma-1 Receptors

JOURNAL OF PALLIATIVE MEDICINE, 2015;

FI:1,912; Q2

Maternal PPARG Pro12Ala polymorphism is associated with infant’s neurodevelopmental outcomes at 18 months of age

EARLY HUMAN DEVELOPMENT, 2015;

FI:1,785; Q2

Seroprevalence of Leishmania infection among asymptomatic renal transplant recipients from southern Spain

TRANSPLANT INFECTIOUS DISEASE, 2015;

FI:2,064; Q3

Sigma-1 receptor and inflammatory pain

INFLAMMATION RESEARCH, 2015;

FI:2,347; Q3

Evaluación de la Eficacia Analgésica de Un Nuevo Sistema Electromagnético Transcutáneo en Patologías Asociadas A Dolor Neuropático Periferico

Financiador: CONSEJERÍA DE SALUD

Número de expediente: PIN-0505-2016

Tiempo de ejecución: 01/01/2017 - 31/12/2018

IP: RAFAEL GALVEZ MATEOS

Estudio aleatorizado, doble ciego, controlado con un placebo y en grupos paralelos para evaluar la eficacia y la seguridad del BIIB074 ensujetos condolor neuropatico por radiculopatia lumbosacra

Financiador: CONVERGENCE PHARMACEUTICALS LIMITED

Tipo de prueba: ENSAYO CLINICO COMERCIAL

Tiempo de ejecución: 20/04/2017 - 30/05/2018

IP: RAFAEL GALVEZ MATEOS

An Uncontrolled, Open-Label Extension Study to Evaluate the Long-Term Safety, Tolerability, and Maintenance of Effect of BIIB074 in Subjects With Neuropathic Pain From Lumbosacral Radiculopathy

Financiador: BIOGEN IDEC LIMITED

Tipo de prueba: ENSAYO CLINICO COMERCIAL

Tiempo de ejecución: 08/11/2017 - 30/04/2019

IP: RAFAEL GALVEZ MATEOS

Ensayo doble ciego, controlado con placebo, aleatorizado, de busquedad de dosis para determinar la seguridad y eficacia de tres niveles de dosis de EMA401 para reducir la puntuacion de intensidad del dolor promedio a las 24 horas en pacientes con neuralgia posherpetica (EMPHENE)

Financiador: NOVARTIS FARMACEUTICA, S.A.

Tipo de prueba: ENSAYO CLINICO COMERCIAL

Tiempo de ejecución: 21/07/2017 - 30/09/2019

IP: RAFAEL GALVEZ MATEOS