TEC12-Biomecánica
Terapias avanzadas y Tecnologías Biomédicas / IBS-TEC12
The structural microarchitecture of soft tissue is recently becoming a cornerstone of biomechanical engineering and is of growing interest for a broad spectrum of clinical specialists. Our new ultrasonic wave concepts are enabling a new class of biomarkers for both imaging and controlling in vivo and noninvasively tissue microarchitecture. The breakthrough of modelling its elastic hierarchical complexity impacts critical aspects including organ-level functionality, inflammatory and healing processes, tumour growth, all the way down to cell-to-cell signalling. We have: a) Conceived and developed torsional ultrasonic waves and sensor technologies capable of generating and sensing them, prototyping robust functional instrumentation. b) Modelled relationships between the biochemical cascade and the mechanical functionality and their interaction with ultrasound, integrating models of tissue remodelling and tumour growth, experimentally validated by ultrasonication of cancer stem cells.
Líneas de investigación
- Biomecánica y ensayos mecánicos de tejidos
- Biorreactores sensorizados
- Dispositivos médicos de diagnóstico por ultrasonidos y elastografía - aplicación a parto pretérmino
- Ecografía elastográfica y de ultra-alta velocidad
- Inferencia estadística, inteligencia artificial, pronóstico, decisiones, imagen
- Modelos computacionales biomecánicos - elementos finitos
Palabras clave
Ultrasonidos, Ecografía, Ginecología, Elastografía, Biomecánica, Ensayos mecánicos, Ginecología, Oncología, Ondas, Biorreactores.
YOUSEF ALMASHAKBEH SALEH
PARISA REZAEIAFARAPOLI
HIRAD SHAMIMI NOORI
OLGA OCON HERNANDEZ
CARMEN PADILLA VINUESA
MIGUEL ANGEL RIVEIRO TABOADA
GUILLERMO RUS CALBORG
JORGE TORRES PEREZ
BEATRIZ BLANCO BESTEIRO
ANTONIO CALLEJAS ZAFRA
PILAR CARRETERO LUCENA
ANTONIO GOMEZ FERNANDEZ
OTILIA RUTH GONZALEZ VANEGAS
INAS H FARIS
MANUEL HURTADO ESTEVEZ
JUAN MANUEL MELCHOR RODRIGUEZ
FRANCISCA SONIA MOLINA GARCIA
Biomechanical Constitutive Model Identification
MATHEMATICAL PROBLEMS IN ENGINEERING, 2019;
FI:1,179; Q3
News from cedille (evaluation, deadlines, statistics, databases, panel of evaluators …)
CEDILLE-REVISTA DE ESTUDIOS FRANCESES, 2019;
Experimental Configuration to Determine the Nonlinear Parameter in PMMA and CFRP with the Finite Amplitude Method
SENSORS, 2019;
FI:3,031; Q1
In Vivo Measurement of Cervical Elasticity on Pregnant Women by Torsional Wave Technique: A Preliminary Study
SENSORS, 2019;
FI:3,031; Q1
Association of sedentary time and physical activity during pregnancy with maternal and neonatal birth outcomes. The GESTAFIT Project
SCANDINAVIAN JOURNAL OF MEDICINE & SCIENCE IN SPORTS, 2019;
FI:3,631; Q1
Effect of Contact Conditions of Torsional Wave Elastographic Probe on Human Cervix
MATHEMATICAL PROBLEMS IN ENGINEERING, 2018;
FI:1,145; Q3
Aspirin Versus Placebo in Pregnancies at High Risk for Preterm Preeclampsia
OBSTETRICAL & GYNECOLOGICAL SURVEY, 2018;
FI:2,014; Q3
Logical Inference Framework for Experimental Design of Mechanical Characterization Procedures
SENSORS, 2018;
FI:2,475; Q1
First-line mFOLFOX plus cetuximab followed by mFOLFOX plus cetuximab or single-agent cetuximab as maintenance therapy in patients with metastatic colorectal cancer: Phase II randomised MACRO2 TTD study
EUROPEAN JOURNAL OF CANCER, 2018;
FI:7,191; Q1
Association of General and Abdominal Obesity With Hypertension, Dyslipidemia and Prediabetes in the PREDAPS Study
REVISTA ESPANOLA DE CARDIOLOGIA, 2018;
FI:5,166; Q1
Poly(ethylmethacrylate-co-diethylaminoethyl acrylate) coating improves endothelial repopulation, bio-mechanical and anti-thrombogenic properties of decellularized carotid arteries for blood vessel replacement
SCIENTIFIC REPORTS, 2017;
FI:4,259; Q1
Maternal BMI and gestational diabetes alter placental lipid transporters and fatty acid composition
PLACENTA, 2017;
FI:2,759; Q1
Doppler assessment of patients with twin-to-twin transfusion syndrome and survival following fetoscopic laser surgery
INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS, 2017;
FI:2,174; Q2
Data quality in rare cancers registration: the report of the RARECARE data quality study
TUMORI, 2017;
FI:1,233; Q4
ASPRE trial: performance of screening for preterm pre-eclampsia
ULTRASOUND IN OBSTETRICS & GYNECOLOGY, 2017;
FI:4,71; D1
Torsion ultrasonic sensor for tissue mechanical characterization
2016 IEEE INTERNATIONAL ULTRASONICS SYMPOSIUM (IUS), 2016;
Use of shear waves for diagnosis and ablation monitoring of prostate cancer: a feasibility study
14TH ANGLO-FRENCH PHYSICAL ACOUSTICS CONFERENCE (AFPAC2015), 2016;
Three dimensional ultrasonography for advanced neurosonography (Neurosofe-3d). Analysis of acquisition-related factors influencing the quality of the brain volumes
PRENATAL DIAGNOSIS, 2016;
FI:3,043; Q1
Layered material characterization using ultrasonic transmission. An inverse estimation methodology
ULTRASONICS, 2016;
FI:1,954; Q1
Maternal Body Weight and Gestational Diabetes Differentially Influence Placental and Pregnancy Outcomes
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2016;
FI:5,531; Q1
Dispositivo de diagnóstico de cáncer de próstata por ondas mecánicas.
Financiador: FUNDACIÓN PÚBLICA PARA LA INVESTIGACIÓN BIOSANITARIA DE ANDALUCIA ORIENTAL ALEJANDRO OTERO (FIBAO)
Número de expediente: INB-0010
Tiempo de ejecución: 10/06/2017 - 09/06/2019
IP: GUILLERMO RUS CALBORG
PI16/00339 PREDICCIÓN DEL PARTO POR ELASTOGRAFÍA ULTRASÓNICA
Financiador: INSTITUTO DE SALUD CARLOS III
Número de expediente: PI16/00339
Tiempo de ejecución: 01/01/2017 - 31/12/2019
IP: FRANCISCA SONIA MOLINA GARCIA
Ultrasonidos de Torsión para Diagnóstico de Parto Pretérmino y Predicción del Éxito en la Inducción.
Financiador: CONSEJERÍA DE SALUD
Número de expediente: PI-0107-2017
Tiempo de ejecución: 01/01/2018 - 31/12/2020
IP: JUAN MANUEL MELCHOR RODRIGUEZ
Dispositivo para Predicción de Parto Mediante el Desarrollo Tecnológico de Un Sensor Ultrasónico de Torsión.
Financiador: CONSEJERÍA DE SALUD
Número de expediente: PIN-0030-2017
Tiempo de ejecución: 01/01/2018 - 31/12/2020
IP: Dispositivo para Predicción de Parto Mediante el Desarrollo Tecnológico de Un Sensor Ultrasónico de Torsión.
Impacto de la detección y tratamiento precoz de las gestantes portadoras asintomáticas de vaginosis bacteriana, en la tasa de parto pretérmino (VB-PREM)
Financiador: INSTITUTO DE SALUD CARLOS III
Número de expediente: PI17/01881
Tiempo de ejecución: 01/01/2018 - 31/12/2020
IP: OTILIA RUTH GONZALEZ VANEGAS